Celiac Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Celiac Disease, including details on symptoms, diagnosis, causes, diet.

Anti-brain but not celiac disease antibodies in Landau-Kleffner syndrome and related epilepsies.

Boscolo S, Baldas V, Gobbi G, Giordano L, Cioni G, Not T, Ventura A, Tongiorgi E

BRAIN Centre for Neuroscience, Department of Biology, University of Trieste, Via L. Giorgieri 10-34127, Trieste, Italy.

The Landau-Kleffner syndrome, the continuous spikes-waves during slow sleep syndrome and the benign epilepsy of childhood with rolandic spikes are rare childhood epilepsies with unknown etiology. Improvement in patients treated with immunoglobulin suggests an involvement of the immune system. We provide immunohistochemical evidence of autoantibodies against rat brain auditory cortex, brainstem and cerebellum, in children suffering with one or more of these syndromes. Only 1/14 patient was celiac.

Published 15 February 2005 in J Neuroimmunol, 160(1): 228-32.
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