Celiac Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Celiac Disease, including details on symptoms, diagnosis, causes, diet.

Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia.

Wilkinson ID, Hadjivassiliou M, Dickson JM, Wallis L, Grünewald RA, Coley SC, Widjaja E, Griffiths PD

Academic Unit of Radiology, University of Sheffield, Sheffield, England. i.d.wilkinson@shef.ac.uk

Gluten sensitivity can manifest with ataxia. The metabolic status of the cerebellum was investigated in 15 patients with gluten ataxia and 10 controls using proton MR spectroscopy. Significant differences were present in mean N-acetyl aspartate levels at short echo time and N-acetyl aspartate/choline ratios at long echo time between the patient and control groups. These data support the hypothesis that cerebellar neuronal physiology differs between patients with gluten ataxia and healthy controls.

Published 20 June 2005 in J Neurol Neurosurg Psychiatry, 76(7): 1011-3.
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